Onder andere met: Jessica Biel (Erin), Jonathan Tucker (Morgan), Erica Leerhsen (Pepper), Mike Vogel (Andy), Eric Balfour (Kemper), Andrew Bryniarski (Thomas Hewitt (Leatherface)), R. Lee Ermey (Sheriff Hoyt), David Dorfman (Jedidiah), Lauren German (Teenage Girl), Terrence Evans (Old Monty), Marietta Marich (Luda May), Heather Kafka (Henrietta), Kathy Lamkin (Tea Lady in Trailer), Brad Leland (Big Rig Bob), Mamie Meek (Clerk)