Onder andere met: Milla Jovovich (Alice), Michelle Rodriguez (Rain Ocampo), Kevin Durand (Barry Burton), Sienna Guillory (Jill Valentine), Oded Fehr (Carlos Oliveira), Li Bingbing (Ada Wong), Shawn Roberts (Albert Wesker), Johann Urb (Leon Kennedy), Boris Kodjoe (Luther West), Colin Salmon ( James „One“ Shade)