Onder andere met: Jamie Foxx (Django Freeman), Christoph Waltz (Dr. King Schultz), Leonardo DiCaprio (Calvin Candie), Kerry Washington (Broomhilda Von Shaft), Samuel L. Jackson (Stephen), Don Johnson (Spencer 'Big Daddy' Bennett), Walton Goggins , Dennis Christopher , James Remar , David Steen , Dana Michelle Gourrier (Cora), Nichole Galicia (Sheba), Laura Cayouette (Lara Lee Candie-Fitzwilly), Ato Essandoh (D'Artagnan), Sammi Rotibi , Clay Donahue (Fontenot), James Russo , Don Stroud , Bruce Dern , Franco Nero (Amerigo Vessepi)