Onder andere met: Ilona Massey (Baroness Elsa Frankenstein), Patric Knowles (Dr. Mannering), Lionel Atwill (Mayor), Bela Lugosi (The Frankenstein Monster), Maria Ouspenskaya (Maleva), Dennis Hoey (Inspector Owen), Don Barclay (Franzec), Rex Evans (Vazec), Dwight Frye (Rudi), Harry Stubbs (Guno), Lon Chaney Jr. (The Wolf Man (as Lon Chaney))